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It may reduce the absorption of oral medications by interacting with intestinal transporters, potentially affecting the bioavailability of drugs like metformin

10.1016/j.ecl.2020.02.009 33 HolladayC.AbbahS

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Astrocytes also regulate the neuronal excitability by modulating tonic N -methyl-D-aspartate (NMDA) receptor currents, by releasing glycine and contributing to extracellular level of D-serine, both being allosteric co-agonists of NMDA receptors through the release of glutamate and contributing to extracellular levels of NMDA receptors 82,83
