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Our study sample was substantially increased to take into account potential dropouts, any unexpected increase in variability, and the use of multivariate statistical analyses
Furthermore, another component of the API complex, FOSL1, is highly expressed in IPSC-derived motor neurons from SOD1 patients carrying the E100G mutation (Bhinge et al., 2017) compared to isogenic controls, suggesting that the AP1 complex is a driver for neurodegeneration
10.1016/j.lfs.2019.116927 118

Golshan et al., 2025