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Other abnormalities include the accumulation of ectopic lipid metabolites that later impair mitochondrial oxidative phosphorylation and reduce insulin-stimulated mitochondrial ATP production, and also generate reactive oxygen species (ROS) [68]
Finally, compounds that form insoluble aggregates can cause interference by scattering light from both the excitation and/or emission wavelengths
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Chronic infection stimulates lymphocyte proliferation and antigenic response, contributing to antibody formation and cell-mediated immunity (62)
