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Description
NNMT sits between NAD+ metabolism and one-carbon methylation metabolism, pathways that support redox reactions, DNA repair, and transcriptional regulation
This creates two downstream problems: (1) SAM depletion reduces the availability of methyl groups for other critical methylation reactions, including DNA and histone methylation
Administration Technique: For injectable forms, proper subcutaneous injection technique, site rotation, and sterile handling minimize the risk of injection site reactions or infections
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