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Adsorptive-mediated transport at the BBB has also been exploited to target nanocarrier systems by using cationic lipids and cell penetrating peptides to increase binding and internalization at the brain capillary endothelium [29, 30], which has a highly negative surface charge [31]

MichaelisMenten kinetics Nanozymes frequently exhibit enzyme-like MichaelisMenten kinetics, which is regarded as a key feature of their biocatalytic behavior

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