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DOI: 10.1073/pnas.0409481102 Stedman, C.A., Liddle, C., Coulter, S.A., Sonoda, J., Alvarez, J.G., Moore, D.D., Evans, R.M., Downes, M
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We pay more attention to small molecule compounds which influence the progress of Cu-induced cell death, rather than transcription factors, ncRNAs or other types of regulators, since they are more readily screened and dosed to produce therapeutic outcome than other types of candidates
Just equilibrating isolated mitochondria to pH 8.8 then adding acid to the external medium to give a pH of about 4.3 can generate ATP [5]
