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Furthermore, lipid metabolic reprogramming in M2-like TAMs promotes immunosuppressive cytokine release and Treg recruitment, which are tightly linked to non-response to ICIs
Nonetheless, all SOD isoforms (Cu/Zn-SOD, Mn-SOD, Fe-SOD) are nuclear-coded and are transported to their organellar locations via NH 2 -terminal targeting sequences when necessary (Sharma et al., 2012)
International Immunopharmacology 7: 333342
