glutathione deficient rbcs Inherited Reductase Deficiency and Plasmodium falciparum Malaria—A Case Study Reduced glutathione level and G6FG
Description
So is considered well-tolerated and safe

Semaglutide is a GLP-1 receptor agonist that suppresses appetite, delays gastric emptying, and improves glucose-dependent insulin secretion

View on PubMed Seiwerth S, Brcic L, Sila D, et al
This means any small, cumulative toxic exposures can cause that cup to overflow