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Niacin (nicotinic acid) has been classified as pregnancy category C
It has also been shown to influence lipid metabolism enzyme activity, including hormone-sensitive lipase and lipoprotein lipase, and to modulate adipogenic transcription factor expression in adipocyte differentiation models
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The signaling through these pathways induces expression of corticotrophic-releasing hormone (CRH) and thyrotrophin-releasing hormone (TRH) [5]
