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Arsenic exposure in Indo Gangetic plains of Bihar causing increased cancer risk
Ahmadi P, et al
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a tetrameric cytosolic enzyme that catalyzes the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate in the payoff phase of glycolysis
Therefore, the robust assignment of ferroptosis should involve coupling of lipid-peroxidation readouts with rescue by lipophilic radical-trapping antioxidants or iron chelators and evidence of GPX4/system Xc contribution
