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In some embodiments, the formulations or compositions described herein have a pH and osmolarity as described herein, and have a concentration of active pharmaceutical ingredient between about 1 M and about 10 M, between about 1 mM and about 100 mM, between about 0.1 mM and about 100 mM, between about 0.1 mM and about 100 nM

has traditionally been used as an eyewash to address and prevent a range of eye conditions, including conjunctivitis, blepharitis, eye fatigue, purulent ocular inflammation, and styes [170]

(A,B) Immunostaining and cell counting results showed that co-treatment with 10 M BAY11-7082 effectively increased the number of surviving SGNs after peroxynitrite damage, while the co-treatment with 5 M or 20 M BAY11-7082 showed no significant differences in SGN number compared to the peroxynitrite-only group

Lee, L.-J