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Initially, we find that expression of G2019S LRRK2 or WT ArfGAP1 alone markedly and equivalently reduce neurite length by 3540% compared to WT LRRK2 or control (empty vector) neurons (Figure 5)

2021;20:e13337

Notably, 87.5% maintained improvement beyond six months, whereas hyaluronic acid injections typically provide relief for just 14 weeks
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