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Wound-healing factors secreted by epidermal keratinocytes and dermal fibroblasts in skin substitutes
Increasing BH 4 supply Rationale As reviewed above, BH 4 deficiency is a common cause of eNOS uncoupling in many cardiovascular diseases (Figure 5) (Vasquez-Vivar et al., 1998
Such studies remind us that negative or nuanced outcomes are often the most enlightening, pushing the field forward and helping refine both scientific questions and clinical practice
However, upon TCR/CD28 co-stimulation of murine Treg, loss of Gpx4 resulted in excessive lipid peroxidation and subsequent ferroptosis
