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The NOAEL for an increase in prostate inflammation on PND 120 was 12.5 mg/kg/day

Photostability evaluation To test the photostability in buffer and cell culture media, PLGA nanoparticles encapsulating DDA-GSH-AuNCs in water (2 mg/mL) was mixed with water (control), PBS or DMEM that contains 10% FBS (final concentration of PLGA nanoparticles is 0.5 mg/mL and AuNCs 4 g/mL as gold)

Then, the virus- encoded trans-activator Tat is produced and triggers explosive viral replication
