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A 2025 systematic review in Orthopaedic Sports Medicine analyzed 36 studies on BPC-157 and found that the peptide improved functional, structural, and biomechanical outcomes in muscle, tendon, ligament, and bone injury models

v It took Searle, the manufacturer, 16 years to get aspartame approved as a food additive in the United States, and they were under investigation for performing fraudulent studies
