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Overall, the ongoing advancement of therapeutic strategies for CRC, particularly within the framework of LS, underscores the necessity of personalized treatment modalities customized to the distinct genetic and molecular attributes of tumors, thereby enhancing patient outcomes and survival probabilities

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Mutations in either of the two EF-hand subunits of the MCU complex encoded by the MICU1 and MICU2 genes have been identified in humans

Interactions of zinc-and redox-signaling pathways
