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75 Mitochondrial dysfunction is characterized by decreased ATP and increased oxygen free radical production and is a common underlying feature of chronic and age-related conditions

The dimerization of the MlaF engages the CHs between TM2 and TM3 of MlaE, which induces the rearrangement of all TMs
is an investigator at the Howard Hughes Medical Institute

This change, while seemingly minor, altered the pharmacological profile to favor central MC4R-mediated sexual function effects while reducing some peripheral activities
