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ALA has been evaluated in the treatment of multiple sources of neuropathic pain, including chemotherapy-induced peripheral neuropathy, entrapment neuropathies, radicular nerve pain, and burning mouth syndrome

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( A ) Schema of monoallelic CRISPR editing to generate the Mmut p.L690Ins allele with representative Sanger sequencing results for wild-type and Mmut p.L690Ins/p.L690Ins mice