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\n\n\n\n Large-scale human clinical trials are currently lacking

Glucagon's capacity to regulate hepatic glucose metabolism is primarily responsible for its hyperglycemic effects [27]

There are several mechanisms which may underlie the association between type II diabetes and dementia, including neurotoxicity resulting from hyperglycemia, alterations in amyloid metabolism, increased risk of cerebrovascular disease, and a combination of these mechanisms (6)

2.22 illustrates pH-solubility profile for a free acid and free base of weakly acidic and weakly basic drugs
