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As for targeted therapy in cancer metabolism, gain of function mutations in isocitrate dehydrogenases (IDH1 and IDH2) result in the production of the oncometabolite 2-hydroxyglutarate (140, 141)
however, choline comprises only about 13% of the weight of phosphatidylcholine (111)
Al-Nahhas, R
Free Report Blockmans D, Persoons P
