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KrystalJHKarperLPSeibylJPFreemanGKDelaneyRBremnerJDet al

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P-glycoprotein (P-gp/ Abcb1), Abcc2, and Abcc3 determine the pharmacokinetics of etoposide

In particular, GSTP1-1 is able to protect the tumor cells from apoptosis signals by inhibiting c-Jun N-terminal kinase (JNK)a member of the MAPK pathwaynon-catalytically, by direct proteinprotein association 25,26
