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Repairing this intricate, high-stress network is a formidable challenge
When opioids are necessary, FDA-approved naltrexone doses ranging from 50 to 100 mg for the treatment of alcohol- and opioid-use disorder often involve a higher dose to overcome antagonism and cautious titration to take effect
doi: 10.7554/eLife.78469.sa2 74 RotsDChoufaniSFaundesVDingemansAJMJossSFouldsNet al

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