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Body water is controlled on one hand by fluid intake that is stimulated by thirst, and on the other hand by renal excretion of water
Early identification and treatment are crucial, as neurological damage may become irreversible in later stages
Samples were analysed for vinorelbine using a validated HPLC-fluorescence detection method over the concentration range of 2500 ng ml 1 by Bioanalytical Laboratory Service (PPD Development, Richmond, VA, USA)
