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Emergency Reversal Knowing t guides when to redose antidotes or restart monitoring KOTC Mnemonic: Half Gone by Half-Time Imagine a timer counting down drug effect

Nat Rev Drug Discov 21 , 578600 (2022)

Foods and supplements that help synthesis Glutathione production include: Sulfur-rich (sulforaphane) foods like cruciferous vegetables, including broccoli, kale, collards, cauliflower, and brussel sprouts More sulfur-rich are from the ALLIUM family like onions, garlic, shallots, and leeks Vitamin C foods like strawberries, grapefruit, oranges, papayas, kiwi Whole grains contain all the amino acids Tofu and tempeh Kombu Lentils Sunflower seeds N-AC (N-acetyl cysteine)- a form of the amino acid that helps build the Glutathione Glycine Glutamic acid Some foods that contain Glutathione include: Avocadoes (these are an excellent source of Glutathione

Findings: Preclinical data demonstrated extended GH and IGF-1 elevation due to DAC binding, supporting prolonged biological activity
