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However, a much repeated criticism of studies of MSG taken without food is that the characteristic strong flavor of MSG is difficult to mask, unblinding the subjects to its identity and potentially leading to bias. Even in people who self-identify as MSG sensitive, studies have failed to provide reproducible evidence of an MSG effect. The authors of the largest and most comprehensive of such studies concluded that large doses of MSG given without food may elicit more symptoms than a placebo in individuals who believe that they react adversely to MSG

Cholangio refers to the biliary system: the bile ducts in the liver, the gall bladder that stores digestive fluid called bile which is produced in the liver, and the duct that delivers the bile into the duodenum or the upper-most section of the small intestine