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First, because 4MP causes considerable phospho-JNK inhibition which negatively impacts p53 activation and necrosis 92 , we considered that 4MP causes a conservative 80% decrease of p53 activation and simulated this by multiplying the phosphorylation rate of p53 with parameter k 4MP JNK = 0.2 (i.e., decreasing the phosphorylation rate)

How to Maximize Glutathione Absorption Cooking methods significantly impact the glutathione content and bioavailability of foods

Rapid deproteinization using acidic solutions (MPA, PCA, or trichloroacetic acid) immediately upon sample collection prevents enzymatic degradation and spontaneous oxidation

doi: 10.1038/nchembio.283