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Description
As protein homeostasis deteriorates with age, UPR is directly linked to the longer lifespan 6,39
Xiao Q, Zhao W, Beers DR, Yen AA, Xie W, Henkel JS, Appel SH: Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia
For instance, several microbes synthesize modified versions of GSH or have even replaced GSH with distinct but redox-similar analogs [63]
Glutathione is a critical Phase II detoxification agent, meaning glutathione attaches to lipid-soluble toxins to make them more easily excreted from the body
