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Nef also activates NADPH oxidase through the Vav/Rac/PAK pathway in phagocytes, amplifying neuroinflammation and promoting myelin injury and neuronal damage [134, 140]
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doi: Ebrahimi, B

These observations underscore the notion that personalized and preventive nutritional strategies can effectively complement exercise-oriented therapies to address the molecular underpinnings of sarcopenia rather than merely alleviating its superficial manifestations
