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For instance, ethanol intake is known to activate CYP3A, CYP1A2 and CYP2B in the liver (and the extra-hepatic tissues) [104], probably resulting in increased production of reactive MDMA metabolites [Fig
Therefore, inhibition of xanthine oxidase is expected to delay the loss of hypoxanthine in the form of uric acid, thus favoring the restoration of nucleotide levels via IMP and guanine (Camina et al., 1995)
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Hingston, J
