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It is indicated for treating vitaminB12 deficiency in conditions such as pernicious anemia, dietary deficiency, and malabsorption syndromes, as well as for use in diagnostic procedures like the Schilling test

doi: 10.1016/j.ccell.2024.08.011 85 YangDLiuJQianHZhuangQ

It's also worth keeping expectations realistic this is a supportive skincare step, not a quick fix for pigmentation

47 Evidence shows that transcobalamins can suppress systemic inflammation by modulating certain cytokines (ie, interleukin-6), growth factors and other substrates with anti-inflammatory properties under normal physiological conditions
