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Kavaljit H
In experimental settings, the three specific pesticides identified (2,4-dichlorophenoxyacetic acid, paraquat, and permethrin) all have effects on dopaminergic neurons
The cGMP that is produced via NO activation of soluble guanylate cyclase (sGC) in this tissue is degraded by a specific cyclic nucleotide phosphodiesterase (PDE) identified as PDE5A
