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Outcomes Co-primary endpoints were percentage change in body weight from baseline to week 104 and achievement of weight loss of at least 5% of baseline weight at week 104

doi: 10.1155/2021/9924314

The studies documented that fat mass reduction occurred without corresponding changes in lean tissue mass

The AOD9604 mechanism of action involves binding to beta-3 adrenergic receptors on fat cells, triggering a cascade of intracellular events that activate hormone-sensitive lipase (HSL)