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(2020) described above a shortage of GPX4 bioavailability in erythroblasts may impair enucleation, which fits with the presence of nucleated red cells in the peripheral blood of PKD patients
15 The plasma concentration of GSH is low because of its rapid turnover, and more than 80% of plasma GSH is removed by the kidney
doi: 10.1093/ndt/14.3.738
15: Pearce RK, Owen A, Daniel S, et al
