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Amyotrophic Lateral Sclerosis The primary characteristic of the deadly neurodegenerative disease known as ALS is the selective degeneration of both the brain's upper and lower motor neurons as well as those in the brain stem and spinal cord [247, 248]
J Cell Biol 218(8):25832599 Chen Y, Azad MB, Gibson SB (2009) Superoxide is the major reactive oxygen species regulating autophagy
The conventional route of fortification of food, Oral supplements and I/M injection continue to dominate the therapy regime
These studies primarily rely on preclinical (animal) data and limited early-stage human pilot studies
