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Thus, hyperhomocysteinemia-induced NLRP3 inflammasome activation is mainly through ROS generation, cholesterol biosynthesis, and generation of oxLDL
Notably, lactate-derived lactylation correlates with higher S-AKI incidence and poor prognosis in clinical sepsis patients
Given the lack of curative treatments, substantial resources have been invested in research and clinical trials to develop new therapies
Furthermore, GSEA of each type revealed metabolic gene sets within the top five enrichments for adipose tissue, HEK cells, and skeletal muscle (Fig
