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doi:10.1016/j.gofs.2023.06.001

MiRNAs consist of a highly complex network with their gene targets [71]

Thus, the prolonged presence of immunosuppressive Tregs may contribute to complications of liver disease even in the long-term after HCV cure potentially including, high susceptibility to re-infection, lack of protective immunity after DAA-induced HCV clearance, or possibly a persisting increased risk for liver cancer