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Chen et al., Ultrasound-responsive neurotrophic factor-loaded microbubble- liposome complex: preclinical investigation for Parkinsons disease treatment

Despite the availability of pharmacological, non-pharmacological, and surgical treatments, including brain, spinal, and vagus nerve stimulators, patients continue to experience progressive weakness, and no treatment has yet succeeded as a true disease modifier [13]

Furthermore, due to its rigid, fibrous nature, large quantities of chitin can lead to reduced protein absorption or incomplete digestion by interfering with the digestion of proteins and other macromolecules in the stomach 38