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ALA is preferentially absorbed by pilosebaceous units, and sebocytes metabolize ALA to light-sensitive protoporphyrin IX (PpIX).[65,66] When exposed to light at a suitable dose and wavelength, PpIX forms cytotoxic free radicals that result in cell destruction and apoptosis of sebocytes
The mean is plotted and bars represent the 95% confidence intervals and ** indicates p0.001 by one way ANOVA comparing glo-3(kx38) to wild type
Q-switched lasers: Effective for targeting melanin Pico lasers: Short pulses for minimal damage Cryotherapy Cryotherapy freezes the affected area to reduce pigmentation
