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Description
Actoxumab, a monoclonal antibody targeting repeats within the CROPs domain of TcdA to block its binding, showed limited efficacy in clinical trials [230,231]
Light-sheet imaging was carried out using a custom-built Light Sheet Fluorescence Microscope (Cambridge University Imaging Centre, CUIC, Cambridge, UK) and using an omicron laser combiner with excitation at 488 nm for YFP and 638 nm for Alexa 647
Apo A-I is the core structural protein and each HDL particle may contain multiple Apo A-I molecules
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