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They are used in some research trials

Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Edition (SCID-I/P, Version 2.0)
Mucus acts both as a clearance mechanism through ciliary action and cough expulsion as well as a physical barrier blocking access to the epithelial layer

The pH of a solution can be monitored using an acidbase indicator, a substance that undergoes a color change within a specific pH range that is characteristic of that indicator