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The intestinal microbiota can metabolize phosphatidylcholine to trimethylamine
The 12 mg group achieved 24.2% weight loss at 48 weeks in Phase 2, and 28.7% at 68 weeks in the Phase 3 TRIUMPH-4 trial
Corpus callosum demyelination is detectable by histology and magnetic resonance imaging (MRI) in MS patients [65]
