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Unlike synthetic carriers, they are less likely to trigger immune responses

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The ligandin function of GSTs Because of exhibiting a ligand binding function, glutathione tranferases, have been known as ligandin, a function, which involves the noncovalent binding of nonsubstrate hydrophobic ligands such as heme, bilirubin, various steroids, and conceivably some lipophilic anticancer drugs as well

209,213,214,215 Moreover, in Atox1 / mice, the expansion of extracellular matrix and neointimal formation were inhibited in response to vascular injury, accompanied by decreased accumulation of VSMCs in the neointima and reduced LOX activity