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Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice

Bax protein is a proapoptotic member that acts by forming pores on the mitochondrial outer membrane, allowing cytochrome c to translocate into the cytoplasm, resulting in the loss of energy production and the activation of proteolytic cascade leading to apoptosis (Westphal et al., 2014)

Vitamin C also regenerates glutathione and supports collagen, so the two work as a pair rather than in isolation

doi:10.1042/BJ20111648 Yoshihara E, Masaki S, Matsuo Y, Chen Z, Tian H, Yodoi J (2014) Thioredoxin/Txnip: redoxisome, as a redox switch for the pathogenesis of diseases