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It is therefore plausible that the multidirectional metabolic effects of HBOT on lipid metabolism and adipocyte function are mediated through modulation of all three PPAR isoforms

DT-109 inhibits SMC osteogenic differentiation To elucidate the molecular mechanisms by which DT-109 alleviates aortic calcification and inhibits vascular SMC osteogenic phenotype conversion, we performed in vitro SMC culture studies

SABCS 2016, 2017