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For example, a mutation in the catalytic domain of Nox2 or in the domain responsible for interacting with the other NADPH subunits leads to a total loss of oxidative burst, whereas some mutations in the dehydrogenase domain have no effect on ROS production by phagocytes (Holland, 2013

doi: 10.1021/acs.jproteome.1c00341 281 MrklSButlerMIHollACryanJFDinanTG

29.95 Prices may be subject to local taxes which are calculated during checkout Similar content being viewed by others References Cerutti, P.A

Additionally, the NLRP3 inflammasome pathway mediates both acute and chronic inflammation, and H demonstrates a specific inhibitory effect on its activation (Meyers and Zhu, 2020