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Supplement manufacturers are not required to demonstrate safety or efficacy before bringing products to market, and quality control varies enormously
doi: 10.1186/s13024-020-00368-6 18 AlamMMYangDLiX-QLiuJBackTCTrivettAet al

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IGF1 also enhances the level of mitochondrial protein involved in signal transduction, protein import and folding, mtDNA transcription, and bioenergetics in Huntingtons disease (HD) striatal cells (Ribeiro et al., 2014)
