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Description
Nicotinic acid can cause flushing, itching, and gastrointestinal disturbances at relatively low doses, while nicotinamide has a higher guidance level

Some people may experience slight discomfort, pain or bruising at the injection site for 24-48 hours

In this review, the mechanisms of GPCR desensitization are classified according to their occurrence at the receptor level and downstream to the receptor

Clin Exp Pharmacol Physiol 2006;33:9971001
