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Epithalon was developed in Russia as a synthetic version of epithalamin, a natural peptide produced by the pineal gland

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2 Review analysis methods We analyzed original papers and reviews covering the period from December 2019 to May 2023, published in accessible international databases (Medline, PubMed, and Scopus), with queries for the keywords COVID-19, SARS-CoV-2, sarcoidosis, Treg, follicular Treg, and Treg subsets. Inclusion criteria were as follows: original research with observation of patients with sarcoidosis and COVID-19, meta-analysis, reviews, and research articles