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Oxidative stress is one of the pathogenic factors for glaucoma and the plasma level of GSH is decreased in primary open angle glaucoma including NTG patients 16,17 , supporting suitability of these mouse models for the basic research of NTG 3,15

Food was removed at the start of the test and body temperature was monitored at the indicated time points

Antioxidant enzyme activities and malondialdehyde levels related to aging