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treated people suffering from severe B12 malabsorption with 2,000 g of cyanocobalamin per day (Kuzminski, 1998)

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Mecanismo de accin El mecanismo de 5-Amino-1MQ se centra en la inhibicin selectiva de la nicotinamida N-metiltransferasa (NNMT), enzima que cataliza la transferencia de un grupo metilo desde la S-adenosil-metionina (SAM) hacia la nicotinamida, generando 1-metilnicotinamida (1-MNA) y S-adenosil-homocistena